These data reinforce the
growing awareness that noncoding RNAs are key players in
tumor development by placing miRNAs in a central role in
a well-known tumor-suppressor network. As another tumor
suppressor, Rb gene, there still never had published data
about miRNAs involving its downstream pathway.
In the searching of normal control for the Rb cases, the
situation we met in the study just like that in another mRNA
profiling study of Rb
Identification of miRNAs associated with tumorigenesis
of retinoblastoma by miRNA microarray analysis
Jian-Jun Zhao & Juhua Yang & Jianhong Lin & Nan Yao &
Yihua Zhu & Jianlong Zheng & Jianhua Xu &
Jin Q. Cheng & Jian-Yin Lin & Xu Ma
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